Comparative precision analysis of Precision-controls on automated chemistry analyzers

نویسندگان

  • Aijaz Ahmed
  • Junaid Mahmood Alam
  • Howrah Ali
  • Ishrat Sultana
  • Saima Fazal
چکیده

Background: Automated diagnostic equipments took over manual testing in last three decades, that allowed enhanced reproducibility, precision and accurateness of results; in addition to 24/7 availability of major lab testing profiles. Aim: In this regard, present study described comparative equipments’ precision assessment of conventional chemistry analyzer, Hirachi 912 with Cobas c501 on parametric panels of Preci-controls, both normal (PNU) and pathological (PPU). Materials and Methods: Comparative performance assessment of instruments, the conventional automated Hitachi chemistry analyzer 912 and Cobas c501 (Roche Diagnostics, Basil), was done through analysis of either PNU or PPU, 30 times each on either instruments. For precision, samples for five parameters, creatinine, urea, sugar, total protein and calcium from both PNU and PPU were analyzed by standard methods during January 2015 to Feb 2015. Results: Comparative analysis showed excellent precision correlations among all five parameters on both instruments with R regression ranging from 0.990 to 0.999 for PNU and 0.993 to 0.997 for PPU depicting the precision and reliability of methods, standardization and system equivalency. Conclusion: Regression analysis exhibited nearequivalent data ranging from 84.3% to 99.8%, thus ensuring that standardization and proper calibration of both instruments is upto the mark for routine chemistry analysis of referred parameters.

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تاریخ انتشار 2015